Advanced Organic Chemistry
Formulate a retrosynthetic analysis and propose a total synthesis route for a previously un-synthesized complex natural product.
Apply protecting group strategies in feasible routes to complex natural products and/or other organic molecules of biological or theoretical interest.
Recognize and be able to apply standard methods for carbon-carbon bond forming reactions including: alkylation of nucleophilic carbon; reactions of carbanions with carbonyl groups; reactions involving transition metals; reactions of compounds of boron, silicon, and tin; and cycloadditions.
Recognize and be able to apply standard methods for carrying out the following types of synthetic transformations: reductions of carbonyls and other functional groups, oxidations, electrophilic additions, aromatic substitution reactions.
Predict reaction mechanisms for the reaction types listed in outcomes 3 and 4.