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CHEM 552

Advanced Organic Chemistry

Chemistry and Biochemistry College of Physical and Mathematical Sciences

Course Description

Physical aspects of organic chemistry; mechanisms, reaction intermediates, bonding, stereochemical and stereoelectronic effects, molecular orbital theory, Lewis acidity and basicity.

When Taught

Fall

Grade Rule

Grade Rule 8: A, B, C, D, E, I (Standard grade rule)

Min

3

Fixed

3

Fixed

3

Fixed

0

Other Prerequisites

Chem 462 and 463 (or Chem 468).

Title

Outcome 4

Learning Outcome

Predict reaction mechanisms of major classes of organic reactions, including substitutions, eliminations, additions and radical reactions.

Title

Outcome 5

Learning Outcome

Recognize the impact of non-covalent interactions in complex systems and reaction mechanisms.

Title

Outcome 2

Learning Outcome

Perform calculations using ab initio, semi-empirical, density functional, and molecular mechanics approaches to predict energies and structures of ground and transition states.

Title

Outcome 3

Learning Outcome

Use reaction kinetics, linear free energy relationships, isotope labeling, stereo-electronic effects and stereochemical outcomes to determine reaction mechanisms.

Title

Outcome 1

Learning Outcome

Predict relative energies and locations of frontier molecular orbitals for organic molecules of intermediate complexity using linear combinations of atomic orbitals and hybridized orbital approaches.