CHEM 553
Advanced Organic Chemistry
Chemistry and Biochemistry
College of Physical and Mathematical Sciences
Course Description
Synthetic aspects of organic chemistry; oxidations, reductions, concerted reactions, stereoselectivity, synthetic equivalents, protecting groups. Examples of natural product total synthesis.
When Taught
Winter
Grade Rule
Grade Rule 8: A, B, C, D, E, I (Standard grade rule)
Min
3
Fixed
3
Fixed
3
Fixed
0
Title
Outcome 2
Learning Outcome
Apply protecting group strategies in feasible routes to complex natural products and/or other organic molecules of biological or theoretical interest.
Title
Outcome 5
Learning Outcome
Predict reaction mechanisms for the reaction types listed in outcomes 3 and 4.
Title
Outcome 3
Learning Outcome
Recognize and be able to apply standard methods for carbon-carbon bond forming reactions including: alkylation of nucleophilic carbon; reactions of carbanions with carbonyl groups; reactions involving transition metals; reactions of compounds of boron, silicon, and tin; and cycloadditions.
Title
Outcome 4
Learning Outcome
Recognize and be able to apply standard methods for carrying out the following types of synthetic transformations: reductions of carbonyls and other functional groups, oxidations, electrophilic additions, aromatic substitution reactions.
Title
Outcome 1
Learning Outcome
Formulate a retrosynthetic analysis and propose a total synthesis route for a previously un-synthesized complex natural product.
