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CHEM 489

Structural Biochemistry

Chemistry and Biochemistry College of Physical and Mathematical Sciences

Course Description

Molecular structures of proteins, RNA and DNA as determinants of biological function. Topics include thermodynamics of folding and binding, structural determination, spectroscopy, modeling, protein recognition.

When Taught

Fall

Grade Rule

Grade Rule 8: A, B, C, D, E, I (Standard grade rule)

Min

3

Fixed

3

Fixed

3

Fixed

0

Title

Relate Structure to Biological Function

Learning Outcome

Relate the structure of a macromolecule to its biological function

Title

Structural Information for Biological Macromolecules

Learning Outcome

Describe how X-ray crystallography, nuclear magnetic resonance, cryogenic electron microscopy, and circular dichroism techniques give structural information for biological macromolecules

Title

Communicate Orally and In Writing

Learning Outcome

Communicate scientific ideas (e.g. structure-function relationships) clearly and concisely to others orally and in writing, and use ethical standards in oral and written presentations

Title

Work With Peers

Learning Outcome

Work with peers to answer scientific questions

Title

Motifs and Symmetries in Macromolecular Structures

Learning Outcome

Identify motifs and symmetries in macromolecular structures and chemical interactions that maintain structural integrity