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CHEM 583

Advanced Biochemical Methodology 2

Chemistry and Biochemistry College of Physical and Mathematical Sciences

Course Description

Maintenance and expression of genetic information, the role of nucleic acids in biology at the chemical and structural level, and methods to study and control nucleic acid function as a means of solving biological problems.

When Taught

Winter

Grade Rule

Grade Rule 8: A, B, C, D, E, I (Standard grade rule)

Min

3

Fixed

3

Fixed

3

Fixed

0

Note

One of two required courses for biochemistry graduate students. May be taken before or after Chem 581.

Learning Outcome

Understand methods for studying the structure and function of nucleic acids and methods for manipulating gene expression in living systems.

Learning Outcome

Design appropriate experiments and apply the techniques of nucleic acid biochemistry to their own research problems.

Learning Outcome

Communicate this understanding in both oral and written formats. [

Learning Outcome

Interpret and critique data obtained using these methods as reported in the primary scientific literature.

Learning Outcome

Describe how genetic information is stably maintained, how it is expressed, and how that expression is regulated, with an emphasis on the mechanism by which molecular machines perform these processes.