PSYCH 516

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Neuroimaging Analysis 2: Diffusion Weighted Imaging

PsychologyCollege of Family, Home, and Social Sciences

Course Description

The principles of diffusion weighted image acquisition and how to design, analyze, and interpret diffusion tensor imaging experiments.

When Taught

Winter Even Years

Min

3

Fixed/Max

3

Fixed

3

Fixed

0

Other Prerequisites

Psych 514 (can be taken concurrently) and Psych 515. Or instructor's consent.

Title

1. Principles of Diffusion-Weighted Image Acquisition

Learning Outcome

Students will explain the physical and mathematical principles underlying diffusion-weighted imaging and diffusion tensor modeling, including the assumptions and limitations of commonly used metrics.

Title

2. Diffusion Data Processing and Analysis

Learning Outcome

Students will implement and document a complete diffusion data processing pipeline, including preprocessing, tensor estimation, and tract-based or voxelwise statistical analysis in ways that reflect scientific integrity and respect for research participants.

Title

3. Interpretation of Diffusion Metrics

Learning Outcome

Students will interpret diffusion metrics (e.g., FA, RD, MD) in relation to white matter microstructure, recognizing both the biological inferences and the methodological constraints of these measures.

Title

4. Design of Diffusion-Based Research

Learning Outcome

Students will formulate a theoretically grounded research proposal using diffusion-weighted imaging, articulating clear hypotheses, justified acquisition parameters, and appropriate analytic strategies with attention to ethical stewardship of data and methods.