MMBIO 195
Phage Hunters: Comparative Genomics
Microbiology and Molecular Biology
College of Life Sciences
Course Description
Phage genome annotation. Focus on experimental design and data analysis.
When Taught
Winter
Grade Rule
Grade Rule 8: A, B, C, D, E, I (Standard grade rule)
Min
3
Fixed
3
Fixed
1
Fixed
6
Note
Freshmen or sophomore students preferred. Requires two semester commitment.
Title
Research Presentation
Learning Outcome
Prepare and deliver a research presentation (oral and poster)
Title
Research Abstract
Learning Outcome
Prepare an abstract for a presentation of research data
Title
Research Reading and Writing
Learning Outcome
Gain experience in research writing and reading of scientific papers
Title
DNA Preparation
Learning Outcome
Prepare DNA for sequencing
Title
Bioinformatic Software
Learning Outcome
Learn how to use bioinformatics software for the following:DNA sequence alignment (Consed)Primer design (Primer3)Assessing ORFs for gene calls (GBrowse, Glimmer and GeneMark)Homology assessment (BLAST and Phamerator)Annotation (Apollo)Comparative analysis (positional and functional)
Title
Archiving Samples
Learning Outcome
Archive phage samples and DNA samples (submit archived phage to HHMI)
Title
GenBank
Learning Outcome
Analyze, annotate and prepare to submit genome to GenBank (submit if possible)
